IRM Clinic | Introduction of a new method of genetic research of embryos - comparative genomic hybridization on microarrays (aCGH).

Introduction of a new method of genetic research of embryos - comparative genomic hybridization on microarrays (aCGH).

Dear friends! We are pleased to inform you that the Institute of Reproductive Medicine (IRM) has introduced an innovative method of genetic research of embryos - comparative genomic hybridization on microchips (aCGH).

This method allows you to study with high accuracy all 23 pairs of chromosomes for different genetic pathology until the embryos are implanted into the uterine cavity.
Modern high-tech equipment allows you to select the most promising embryo with a normal set of chromosomes, which will significantly increase the chances of a positive result of the program and the birth of a healthy child.

Comparative genomic hybridization (CGH) is a modern method of molecular genetics that allows you to diagnose chromosomal abnormalities in all chromosomes. The relevance of this problem is that the likelihood of having a child with chromosomal disease increases with age:
• 30 years - 1: 400
• 40 years - 1 : 63
• 45 years - 1: 19.

According to our IRM, after pregnancy in IVF programs, about 20-25% of pregnancies are terminated in the early stages, which in 60% of cases is associated with chromosomal abnormalities of the fetus. Genetic diagnostics using the CGH method makes it possible to identify these embryos and exclude their transfer. Carrying out a genetic study of the embryo also makes it possible to ensure that the born baby will not subsequently be diagnosed with such severe genetic diseases as Down syndrome, Edwards syndrome, Shereshevsky-Turner syndrome, as well as other chromosomal abnormalities, which are characterized by severe mental retardation and the presence of physical malformations.

Today, CGH is the only opportunity to identify chromosomal abnormalities in the embryo, which prevents the birth of a child with chromosomal diseases and increases the effectiveness of IVF to 70-75%

Indications for CGH:
• The medical history already contains one or more “frozen”
pregnancies;
• Habitual miscarriage
• Two or more unsuccessful IVF attempts;
• Mother's age is more than 35 years;
• In case of severe male factor infertility
• The patient has already had a pregnancy with a chromosomal abnormality or the couple already has one child with a chromosomal abnormality;
• One or both parents are carriers of balanced structural chromosomal rearrangements.

Today we are the only clinic in Kazakhstan that makes it possible, within one medical institution, to carry out a full cycle of ART programs with preimplantation genetic diagnosis (PGD) through comparative genomic hybridization.

We strive to use the “gold standard” of preimplantation genetic diagnosis accepted in the world’s leading IVF clinics and help the birth of your dreams!

Introduction of a new method of genetic research of embryos - comparative genomic hybridization on microarrays (aCGH).

Today, CGH is the only opportunity to identify chromosomal abnormalities in the embryo, which prevents the birth of a child with chromosomal diseases and increases the effectiveness of IVF to 70-75%

We strive to use the “gold standard” of preimplantation genetic diagnosis accepted in the world’s leading IVF clinics and help the birth of your dreams!